High Definition Imaging of the GI Tract-Mayo Clinic

Just as cameras and televisions have been reinvented in the last decade with improved optics, sharpness and brightness, so have the tiny imaging scopes that physicians use to peer into the bodys nooks and crannies — its organs and digestive system. Researchers at the Florida campus of Mayo Clinic are testing the power of these new endoscopic optics to potentially help prevent or detect early colon cancer, lung cancer metastasis, and esophageal cancer. Results of a number of these studies, led by Michael Wallace, MD, MPH, professor of medicine, are being presenting at the annual international scientific conference, Digestive Disease Week (DDW) 2010. In one study, for example, gastroenterologists at Mayo have pitted multiple high-tech probes against each other to see how well they detect the tiniest precancerous polyp in the colon. They have determined that one endoscopic imaging tool called the probe-based confocal laser endomicroscopy (pCLE) shows the highest accuracy yet in detecting small precancerous polyps inside the colon wall. The probe is only one-sixteenth of an inch in diameter. We can see detail that was unimagined 10 years ago, says Dr. Wallace. We can zoom in on a potential problem spot in the colon with 1000-fold magnification, leading to a day when we can perform virtual biopsies on patients meaning that we will be able to tell if a lesion is precancerous by looking at it, and if it isnt, we can leave it alone. Now we have to remove anything that looks even ...

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